CCR6 is not necessary for functional effects of human CCL18 in a mouse model
نویسندگان
چکیده
منابع مشابه
CCR6 is not necessary for functional effects of human CCL18 in a mouse model
CCL18, a chemokine with no known receptor, has been implicated in several fibrotic pulmonary diseases associated with T-lymphocyte infiltration. It has been hypothesized that CCL18 may act through CCR6. Gene delivery of human CCL18 to the lungs of wild-type mice induced pulmonary infiltration of T-lymphocytes, less than 5% of which expressed CCR6. In the lungs of CCR6-deficient mice, CCL18-driv...
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ژورنال
عنوان ژورنال: Fibrogenesis & Tissue Repair
سال: 2012
ISSN: 1755-1536
DOI: 10.1186/1755-1536-5-2